What does "neoadjuvant therapy" refer to?

Neoadjuvant therapy refers specifically to treatment that is given before the main or primary treatment, typically surgery, to shrink tumors. This approach is particularly valuable in managing certain cancers, including breast cancer, as it allows for the possibility of less extensive surgery and may improve surgical outcomes. By reducing tumor size prior to surgical intervention, neoadjuvant therapy can help ensure that more complete removal of cancerous tissue is possible and can also provide insight into how the cancer responds to specific treatments, which may guide further therapy decisions.

The choice is significant in cancer management as it emphasizes the proactive strategy of addressing tumors before the primary intervention.